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Question 187 / 280
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CLINICALPATHOLOGY-152
FAECAL OCCULT BLOOD TESTING (FOBT) detects hidden blood in stool. The GUAIAC-BASED test (gFOBT) relies on which chemical principle?
A. Antibody reaction with haemoglobin peptides
B. PSEUDOPEROXIDASE ACTIVITY OF HAEM — haemoglobin catalyses the oxidation of guaiacol to quinone (blue color) in the presence of hydrogen peroxide
C. Precipitation of protein in alkaline conditions
D. Reduction of Benedict's reagent by blood sugar
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