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Question 277 / 280
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CLINICALPATHOLOGY-242
C-REACTIVE PROTEIN (CRP) and PROCALCITONIN (PCT) are acute phase reactants. How do they differ in GUIDING ANTIBIOTIC THERAPY in RESPIRATORY TRACT INFECTIONS?
A. They are identical and can be used interchangeably
B. CRP: general inflammatory marker (rises in bacterial AND viral infections); PROCALCITONIN: more SPECIFIC for BACTERIAL infections (IFN-α suppresses PCT in viral → PCT LOW in viral, HIGH in bacterial). PCT-guided antibiotic use REDUCES unnecessary antibiotic use
C. CRP is only used in autoimmune diseases
D. PCT is used only in pancreatitis diagnosis
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