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Question 82 / 280
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CLINICALPATHOLOGY-47
OLIGOSPERMIA due to Y-CHROMOSOME MICRODELETIONS shows specific regions deleted. Which Y-chromosome region deletion (AZF region) is associated with the WORST prognosis for sperm retrieval?
A. AZFc deletion — poorest prognosis
B. AZFa deletion — associated with complete absence of germ cells (Sertoli-cell-only syndrome)
C. AZFb deletion — associated with maturation arrest
D. AZFc has good prognosis and AZFa has moderate prognosis
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