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Question 115 / 312
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MYCO-028
Aspergillus fumigatus — what is the GALACTOMANNAN ASSAY and what are its LIMITATIONS?
A. Galactomannan detects Aspergillus DNA in blood
B. GALACTOMANNAN ASSAY (ELISA): detects Aspergillus CELL WALL polysaccharide antigen (galactofuranose-containing galactomannan) in SERUM or BAL; LIMITATIONS: false positives from beta-lactam antibiotics (especially piperacillin-tazobactam), enteral nutrition, and Fusarium/Histoplasma cross-reactions; false negatives in patients on antifungals
C. Galactomannan detects ALL fungal infections including Mucor
D. Galactomannan is positive only in Candida infections
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