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Question 179 / 312
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VIRO-060
Human Herpesvirus 6 (HHV-6) — what is its PRIMARY CLINICAL SYNDROME in CHILDREN and which SERIOUS DISEASE does it cause in TRANSPLANT PATIENTS?
A. HHV-6 causes only cold sores; not relevant in transplant
B. HHV-6 in CHILDREN: ROSEOLA INFANTUM (Exanthem Subitum / Sixth Disease) — 3 days of HIGH FEVER then SUDDEN DEFERVESCENCE and MACULOPAPULAR RASH; TRANSPLANT PATIENTS: HHV-6 ENCEPHALITIS/LIMBIC ENCEPHALITIS — altered consciousness, seizures, temporal lobe involvement; CIHHV-6 (chromosomally integrated HHV-6): unique inherited form
C. HHV-6 causes viral hepatitis in children; transplant patients unaffected
D. HHV-6 causes mononucleosis identical to EBV in all ages
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