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qualitycontrol-184
ANALYTICAL VARIABLES — DRUG INTERFERENCE — The text distinguishes between two types of drug interference. What is the difference between METHODOLOGIC and PHYSIOLOGIC drug interference?
A. Methodologic interference occurs before testing; physiologic interference occurs after testing
B. METHODOLOGIC INTERFERENCE: drug detected during measurement AS IF IT WERE the substance of interest (IN VITRO); PHYSIOLOGIC INTERFERENCE: drug received by patient INDUCES AN INCREASE in the substance being measured (IN VIVO biological variation)
C. Methodologic and physiologic drug interferences are the same phenomenon
D. Only methodologic interference affects laboratory results; physiologic interference is insignificant
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